{"id":30820,"date":"2022-12-16T10:46:11","date_gmt":"2022-12-16T11:46:11","guid":{"rendered":"https:\/\/peymantaeidi.net\/stem-cell\/?p=30820"},"modified":"2022-12-16T12:37:12","modified_gmt":"2022-12-16T12:37:12","slug":"local-startup-nanomatronix-receives-1-1-million-small-business-award","status":"publish","type":"post","link":"https:\/\/peymantaeidi.net\/stem-cell\/2022\/12\/16\/local-startup-nanomatronix-receives-1-1-million-small-business-award\/","title":{"rendered":"Local Startup Nanomatronix Receives $1.1 Million Small Business Award"},"content":{"rendered":"
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\nDec. 16, 2022\n <\/p>\n<\/p><\/div>\n

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\n \"Kartik<\/p>\n

<\/a><\/p>\n

\n Photo by University Relations<\/span><\/p>\n

Kartik Balachandran<\/p>\n<\/p><\/div>\n<\/p><\/div>\n

Nanomatronix, a local startup company that develops nanotechnology, microelectronics and biotechnology to provide solutions for the healthcare, energy and defense industries, has been awarded a $1.1 million Small Business Innovation and Research<\/a> Phase II Award from the Department of Defense. This award builds on a previous award from the department.<\/p>\n

The purpose of the award is to continue development of the Advanced Microphysiological Brain Injury Technology (or AMBIT) Platform. This is an organ-on-chip model that utilizes human, cell-based tissues to replicate brain injury pathophysiologies. The chip will enable researchers to model the transport of molecules across the blood-brain barrier before and after traumatic brain injury and examine the communication between different cell types, providing a useful tool for drug screening and toxicity studies.<\/p>\n

Kartik Balachandran, associate professor of biomedical engineering at the U of A, has been overseeing the research and development of the AMBIT Platform and has received a sub-award of $550,000. <\/p>\n

\u201cWe\u2019re excited for the opportunity to further develop our AMBIT Platform towards commercialization and also expand our customer base,\u201d Balachandran said.<\/p>\n

\u201cNanomatronix is excited to collaborate with Dr. Kartik Balachandran to bring AMBIT to market,\u201d said Angeline Rodriguez, a biomedical engineer who will oversee the grant at Nanomatronix. \u201cThe goal of this Phase II project is completion of a viable product and service. Additional evolutionary product improvements are being identified, currently, through the NSF STTR Program. In approximately two to two and a half years, the first full AMBIT product will be ready for launch, and the first batch of products will be delivered to customers.\u201d<\/p>\n

Rodriguez added that what made AMBIT unique was that previously developed brain-chips do not have the ability to mechanically mimic traumatic brain injury in their design. <\/p>\n

\u201cAMBIT is able to provide a TBI-like mechanical insult to study its effects on the blood-brain barrier,\u201d Rodriguez said. \u201cThis platform is relevant for drug discovery and testing in the context of TBI-mediated pathologies and other neurotrauma sequelae. AMBIT is designed using iPSC-derived cells, so it will play an important role in precision medicine because the cellular components can be derived from patient-specific, clinical-grade cells.\u201d <\/p>\n

Rodriguez noted that organ-on-chip technology was revolutionizing the study of diseases, and that Balachandran\u2019s work presented a unique business opportunity to explore technology that can be used to evaluate brain injury pathophysiology.<\/p>\n

The federal Small Business Innovation and Research<\/a> award program incentivizes small businesses to pursue research and development with the potential for commercialization. The goal is for businesses to reach their technological potential and to create a pathway to profitability through commercialization.<\/p>\n

Those interested in Balachandran\u2019s organ-on-chip research, which can replicate a range of organs, can find a fuller treatment on the U of A\u2019s Determined<\/a> website.<\/p>\n

About the University of Arkansas:<\/strong> As Arkansas’ flagship institution, the U of A provides an internationally competitive education in more than 200 academic programs. Founded in 1871, the U of A contributes more than $2.2 billion to Arkansas\u2019 economy<\/a> through the teaching of new knowledge and skills, entrepreneurship and job development, discovery through research and creative activity while also providing training for professional disciplines. The Carnegie Foundation classifies the U of A among the few U.S. colleges and universities with the highest level of research activity. U.S. News & World Report <\/em>ranks the U of A among the top public universities in the nation. See how the U\u202fof\u202fA works to build a better world at Arkansas Research News<\/a>.<\/p>\n

<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

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