{"id":55429,"date":"2025-01-28T13:13:15","date_gmt":"2025-01-28T14:13:15","guid":{"rendered":"https:\/\/peymantaeidi.net\/stem-cell\/?p=55429"},"modified":"2025-01-28T17:37:59","modified_gmt":"2025-01-28T17:37:59","slug":"super-radiance-to-unlock-super-resolution-imaging","status":"publish","type":"post","link":"https:\/\/peymantaeidi.net\/stem-cell\/2025\/01\/28\/super-radiance-to-unlock-super-resolution-imaging\/","title":{"rendered":"Super-radiance to unlock super-resolution imaging"},"content":{"rendered":"<div><\/div>\n<p>To this end, the team from <a href=\"https:\/\/www.rice.edu\/\" target=\"_blank\" rel=\"noopener\">Rice University<\/a>, Texas and <a href=\"https:\/\/www.tamu.edu\/index.html\" target=\"_blank\" rel=\"noopener\">Texas A&amp;M University<\/a> has received a $1.2m award from the&nbsp;<a href=\"https:\/\/www.wmkeck.org\/\" target=\"_blank\" rel=\"noopener\">W.M. Keck Foundation<\/a> to investigate super-radiance\u2019s potential for research and innovation in medicine, engineering and the physical sciences.<\/p>\n<p>Super-resolution imaging (SRI) and single-molecule tracking (SMT) allow scientists to observe molecular-scale processes with extraordinary detail, but these techniques face trade-offs in that achieving higher spatial resolution slows down the imaging process, while faster imaging sacrifices spatial resolution. Moreover, a fundamental limit constrains how precisely individual molecules can be localised.<\/p>\n<p>According to Rice, super-radiance is a phenomenon that occurs when quantum systems such as molecules or nanomaterials collectively emit light in a coordinated and enhanced manner, resulting in greater brightness and faster emission rates. Although this phenomenon has been extensively studied in atomic systems, its application in solid-state and molecular systems remains rare.<\/p>\n<p>\u201cSuper-radiance offers a fundamentally new way to rethink imaging at the molecular level,\u201d said&nbsp;Shengxi Huang, associate professor of electrical and computer engineering and bioengineering at Rice and the research team\u2019s principal investigator. \u201cWe aim to translate this quantum property into a powerful tool for imaging with potential applications in biology, chemistry, physics, [and] engineering.\u201d<\/p>\n<p><a href=\"https:\/\/www.theengineer.co.uk\/news\">MORE FROM NEWS<\/a><\/p>\n<p>The research plan involves the development of fluorophores \u2014 light-emitting chemical compounds \u2014 that can achieve super-radiance. Unlike conventional fluorophores typically used for SRI and SMT that employ individual fluorescent molecules, the new fluorophore design will include aggregates of fluorescent molecules and bundles of carbon nanotubes.<\/p>\n<p>\u201cBy making aggregates of such fluorophores and by achieving super-radiance, we will significantly enhance their brightness and emission rate,\u201d Huang said in a statement. \u201cEngineering super-radiant fluorophores for SRI and SMT could open up unknown worlds with even better spatial resolution and finer temporal resolution.\u201d<\/p>\n<p>The project is highly interdisciplinary, integrating cutting-edge quantum physics with advanced bioimaging techniques. By leveraging super-radiance, the researchers aim to address critical challenges in SRI and SMT, including high-throughput imaging and tracking of molecular processes. These improvements could catalyse breakthroughs across fields such as cell biology, materials science and nanotechnology.<\/p>\n<p>\u201cWith this technology, we could observe cellular mechanisms in real time and with unmatched clarity,\u201d said Huang. \u201cThis opens the door to discoveries we\u2019ve only imagined.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>To this end, the team from Rice University, Texas and Texas A&amp;M University has received<\/p>\n","protected":false},"author":1,"featured_media":55431,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/posts\/55429"}],"collection":[{"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/comments?post=55429"}],"version-history":[{"count":2,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/posts\/55429\/revisions"}],"predecessor-version":[{"id":55432,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/posts\/55429\/revisions\/55432"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/media\/55431"}],"wp:attachment":[{"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/media?parent=55429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/categories?post=55429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peymantaeidi.net\/stem-cell\/wp-json\/wp\/v2\/tags?post=55429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}